McCoy (knee) won't practice Wednesday, ESPN's Mike Rodak reports.

EDGE Analysis

With that in mind, coach Rex Ryan acknowledged that it "doesn't look good" with regard to the running back's chances of playing Sunday against the Jets. While McCoy has yet to be ruled out by the Bills, with the team out of the playoff hunt, there's no compelling reason to push him to play in Week 17. In the event that McCoy remains sidelined for the Bills' season finale, Karlos Williams and Mike Gillislee would once again be in line to handle the team's backfield duties.