Mathis (toe) will not be available for the Cardinals' Week 3 matchup against the Bills, Kent Somers of AZCentral.com reports.

EDGE Analysis

This appears to be a separate injury from the one that put his Week 2 status in question, as Mathis is reportedly now dealing with a turf toe instead of a mid-foot sprain. In his absence, Cole Toner projects to slide into the starting lineup at right guard.