Ramirez (hamstring) is not in the lineup for Game 1 of Wednesday's doubleheader against the Cubs, Mark Sweeney of Fox Sports reports.

EDGE Analysis

Ramirez was lifted from Tuesday night's game due to cramping in his hamstring, but he told the media that he did not expect to miss any time. Regardless, the Padres will hold Ramirez out of Game 1, likely as a precaution, with the possibility that he could be available for the nightcap. Adam Rosales will get the nod at shortstop for the early game, and he'll bat eighth against Chicago's Kyle Hendricks.