Colts coach Jim Caldwell has ruled out MLB Gary Brackett (shoulder) and LB Ernie Sims (knee) for Week 2. The Colts haven't revealed the nature of Brackett's injury, but it's another unneeded blow to an Indianapolis run defense that has no prayer. Look for Pat Angerer to move from the strong side to middle linebacker, where he'll start against the Browns. WLB Kavell Conner is expected to play Sunday, but is battling a bum left foot. Philip Wheeler figures to start at Sam. Peyton Hillis will be the best matchup-play running back in the NFL this week.