The Reds placed Castillo on the family medical emergency list Monday.

EDGE Analysis

Cincinnati had been listing Castillo as its probable starter for Tuesday's series opener against the White Sox in Chicago, but his availability for final week of the regular season is now in question following his deactivation. The team has yet to provide a timeline on Castillo's return to the roster, but he won't be eligible to rejoin the 28-man active roster for at least the next three days. Cincinnati called up Reiver Sanmartin from Triple-A Louisville in a corresponding move ahead of his scheduled start Monday against the Pirates, and he could pick up a second turn through the rotation over the weekend in Pittsburgh if Castillo isn't activated by then.