Jose Reyes SS TOR 57 Mins

Jose Reyes will return to the Blue Jays lineup and his customary leadoff spot for Saturday's game against the Indians.

Reyes has been sidelined since Opening Day due to inflammation in his hamstring. He's been a very valuable fantasy commodity over the years when he's been on the field, though it's unclear how much the hamstring injury will affect his speed and ability to steal bases.

Denard Span CF WAS 1 Hr

Nationals activated OF Denard Span from the 7-day concussion disabled list.

Span is active and will return to the Nationals lineup on Saturday. He reported no issues after a pair of minor league rehab games with Low-A Hagerstown and isn't experiencing any post-concussion symptoms. Fantasy owners can safely insert him back into lineups.

Xander Bogaerts SS BOS 1 Hr

Xander Bogaerts is not in the Red Sox starting lineup on Saturday.

This is the first day of rest that Bogaerts has received this season. The 21-year-old shortstop is off to a strong start to the season, hitting .271/.411/.356 with a homer and three RBI in his first 17 games.

Michael Bourn CF CLE 1 Hr

Michael Bourn is not in the Indians starting lineup for Saturday's contest against the Blue Jays.

Bourn, who returned this week from a hamstring injury, is just 1-for-13 (.077) with five strikeouts and a stolen bases in his first three games. It's likely just a day to rest and clear his head, and he's expected to return to the lineup for Sunday's series finale.

Nate Karns SP TB 1 Hr

Rays prospect right-handed pitcher Nate Karns had his second consecutive good start for Triple-A Durham, striking out nine.

Karns allowed only two hits, one walk, and one hit batsmen in seven shutout innings. Hit ERA sits at an unsightly 5.59 due to two bad starts to start 2014, but in his past two starts he has a 0.75 ERA and opponents are hitting .132/.214/.211 against him. The Rays rotation is beyond overloaded, so Karns would need a couple of injuries to see time in Tampa Bay that is not as a long reliever.

Alex Avila C DET 2 Hrs

It's just a routine day of rest for Avila being a day game after a night game.

Bryan Holaday will get the start behind the dish against opposing southpaw C.J. Wilson. Avila, who is hitting just .182/.308/.242 with no RBI on the season, should return to the lineup on Sunday.

Brandon Nimmo DH NYM 2 Hrs

Mets prospect outfielder Brandon Nimmo went 4-for-5 with a walk and a triple on Friday for High-A St. Lucie.

Nimmo seems to be finding his stroke in 2014, as he is hitting .407/.507/.542 with three doubles, one triple, and one home run through 15 games. Nimmo has 12 walks and 14 strikeouts while making 14 starts in center field. Despite concerns about his range forcing Nimmo into an outfield corner, the Mets are clearly trying to see if Nimmo can find a way to stay in center field.

Brad Boxberger RP TB 3 Hrs

Rays optioned RHP Brad Boxberger from Triple-A Durham.

Boxberger did a very nice job in his three appearances with the Rays, compiling a 2.57 ERA, 0.75 WHIP and 4/2 K/BB ratio in four innings of work. He'll make his way back to the Rays at some point during the season.

Johan Santana SP BAL 3 Hrs

According to Peter Gammons, Johan Santana has seen his velocity slowly climb and isn't far away from being ready to return to the big leagues.

Santana is now up to 85 MPH and continues to make steady progress. He has his sights set on becoming the winningest Venezuelan pitcher of all time, though fantasy owners shouldn't expect much even if he does make his way to the Orioles.

Jimmy Paredes RF KC 6 Hrs

Jimmy Paredes was called up from the minors on Friday April 18.